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UCLA Colorectal Cancer Treatment Program

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Clinical Trials & Research

Clinical Trials & Research

Current clinical trials & research at UCLA Colorectal Cancer Treatment Program.Members of our team are involved in many ongoing clinical and basic science research trials, which will be offered to eligible patients. 

An abbreviated list of current trials include:

Clinical

  • Identifying risk factors (molecular/genetic markers) in the young colorectal cancer patient (<50 years of age).  (Lin, Wainberg)
  • 1st Line Metastatic colon cancer: A Study Evaluating the Efficacy and Safety of MEGF0444A Dosed to Progression in Combination With Bevacizumab and Folfox in Patients With Previously Untreated Metastatic Colorectal Cancer (This study combines a novel monoclonal antibody that blocks an extracellular matrix protein with standard chemotherapy for patients with colon cancer that has spread).
  • 2nd Line metastatic colon cancer: A study evaluating the Efficacy and Safety of GS6624  with FOLFIRI in Patients With Previously Treated Metastatic Colorectal Cancer that is KRAS mutated (This study combines a novel monoclonal antibody that blocks an extracellular matrix protein with standard chemotherapy for patients with colon cancer that has spread and has progressed past front line therapy).

Basic Science

  • Role of Myofibroblasts and PKD in Inflammatory Bowel Disease and Colorectal Cancer (Yoo)
  • Molecular Basis for Racial and Ethnic Disparities in Colon Cancer (in collaboration with investigators from the City of Hope - Yoo)
  • The role of stromal-derived COX-2 by EGF and TNF-α in the setting of colitis-associated cancer (Yoo)

If you are interested in our clinical trials please contact us at (310) 825-0482 for more information. 

 

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